Abstract
A comparative efficacy of Prestokon® and Furazine-II® in the treatment of microbial diarrhea in neonatal lambs over a 24 hour period was evaluated. Microbial Colony Forming Units (CFU) per gram of each faecal sample was determined before treatment and 24 hours after treatment, specific causative microorganisms were not isolated. The average total CFU / g of faeces killed within 24 hours by Prestokon® was 63.31+ 6.22 % and 32.47+14.75 % for Furazine-II®. The clinical response to treatment was also significantly (P < 0.01) better in lambs treated with Prestokon®. Although the result of this study suggest that Prestokon® might be more effective in the treatment of microbial diarrhea in lambs, it must be pointed out that clinically both drugs can be given repeatedly over a period of several days until clinical cure or improvement was observed.
Highlights
New or improved methods of preventing or treating diseases are being tested continually in an effort to improve the health and productivity of animal populations (Williamson, 2002; Constable, 2004; Schoenian, 2009). Disease problems such as microbial infection and endo-parasitism often result in diarrhea, which has a devastating effect on production and productivity (Radostitis et al, 2007)
The average total Colony Forming Units (CFU) / g of faeces killed within 24 hours by Prestokon® was 63.31+6.22 % and 32.47+ 14.75 % for Furazine-II®
Clinical response to treatment was significantly (P < 0.01) better in lambs treated with Prestokon® than those treated with Furazine-II®
Summary
New or improved methods of preventing or treating diseases are being tested continually in an effort to improve the health and productivity of animal populations (Williamson, 2002; Constable, 2004; Schoenian, 2009). Disease problems such as microbial infection and endo-parasitism often result in diarrhea, which has a devastating effect on production and productivity (Radostitis et al, 2007). Neonatal diarrhea is a major cause of losses in all species of farm animals, and caused principally by Escherichia coli, Salmonella species, rotavirus, and Cryptosporidium sp. The purpose of this study was to compare the efficacy of Prestokon® and Furazine-II® in the treatment of microbial diarrhea in neonatal lambs
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