Comparision between laparoscopic hepatectomy and open hepatectomy for recurrent hepatocellular carcinoma

Abstract

Objective To compare the safety and short-term efficacy of laparoscopic repeat hepatectomy (LRH) with open repeat hepatectomy (ORH) for recurrent hepatocellular carcinoma (rHCC). Methods The clinical data of 33 patients with rHCC who underwent hepatectomy at Nanfang Hospital, Southern Medical University from August 2015 to November 2017 were retrospectively analyzed. There were 24 males and 9 females. The patients were divided into LRH group (n=15) and ORH group (n=18). The preoperative clinical data, operative and postoperative data of the two groups were compared. Results No significant differences were observed in the preoperative clinical data of the two groups, including the extent of the previous hepatectomy, the interval between the two surgeries, the number of tumors, and the maximum diameter of tumors. No significant differences were observed in the liver resection method, portal occlusion time and operation duration between the two groups. Blood loss was significantly lower in the LRH group [(66.7±86.1)ml vs. (251.1±75.6)ml, P 0.05). The postoperative diet recovery was significantly shorter (1.2±0.4) days vs. (2.9±1.4) days, the inflammation indicator NEU% was significantly decreased (83.6±4.8)% vs. (88.2±3.7)%, and the length of postoperative hospital stay (6.3±2.9) days vs. (9.8±3.7)days was significantly shorter in the LRH group (P<0.05). Conclusions LRH was safe and effective in the treatment of rHCC, LRH was superior in reducing intraoperative blood loss, promoting postoperative recovery and shortening hospital stay when compared to ORH. Key words: Hepatectomy; Carcinoma, hepatocellular; Recurrence; Laparoscopes