Abstract
Comparing the washout profiles of desflurane in various anesthesia workstations
Highlights
Inhaled halogenated anesthetic agents are commonly used for general anesthesia
Few studies have evaluated the washout kinetics of desflurane, a new volatile anesthetic used in Japan, and no studies have evaluated the washout profiles of desflurane in different anesthetic machines
We evaluated the AisysTM (GE Healthcare), Fabius GSTM (Dräger, Inc., Lubick, German), and Pro-nextTM (Acoma, Inc., Tokyo, Japan) anesthesia workstations, which are used in our operating theater and throughout Japan
Summary
The time required for halogenated anesthetic agents to wash out of the anesthesia workstation, including the ventilator circuit, is an important safety consideration. The washout profiles of anesthesia workstations are useful for predicting patient recovery from general anesthesia. Few studies have evaluated the washout kinetics of desflurane, a new volatile anesthetic used in Japan, and no studies have evaluated the washout profiles of desflurane in different anesthetic machines. Arousal from general anesthesia depends on the blood-gas partition coefficient values, patient factors, and anesthetic-specific factors, it is possible that arousal depends on the respiratory and circulatory circuit volumes of the anesthesia machine. The present study compared the washout profiles for desflurane in various anesthesia workstations that included different types of breathing systems and components. Malignant hyperthermia can be induced by halogenated anesthetics that are inadvertently retained in the anesthetic circuit. We compared the desflurane washout times of three different anesthesia workstations
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