Abstract
BackgroundThe purpose of this study was to investigate the pattern of distribution of risk factors for stroke and the 10-year probability of stroke by the Framingham risk score in hypertensive patients visiting private clinics vs. tertiary hospitals.MethodsA total of 2,490 hypertensive patients who attended 61 private clinics (1088 patients) and 37 tertiary hospitals (1402 patients) were enrolled. The risk factors for stroke were evaluated using a series of laboratory tests and physical examinations, and the 10-year probability of stroke was determined by applying the Framingham stroke risk equation.ResultsThe proportion of patients who had uncontrolled hypertension despite the use of antihypertensive agents was 49% (66 and 36% of patients cared for at private clinics and tertiary hospitals, respectively; p < 0.001). The average 10-year probability of stroke by the Framingham risk score in hypertensive patients was 21% (approximately 2.2 times higher than of the risk of stroke in the Korean Cancer Prevention Study [KCPS] cohort) and was higher in patients attending tertiary hospitals compared to private clinics (16 and 24% of patients attending private clinics and tertiary hospitals, respectively; p < 0.001).ConclusionsSince the 10-year probability of stroke by the Framingham risk score in hypertensive patients attending tertiary hospitals was higher than the risk for patients attending private clinics. We suggest that the more aggressive interventions are needed to prevent and early detect an attack of stroke in hypertensive patients attending tertiary hospitals.
Highlights
The purpose of this study was to investigate the pattern of distribution of risk factors for stroke and the 10-year probability of stroke by the Framingham risk score in hypertensive patients visiting private clinics vs. tertiary hospitals
It has been reported that appropriately treated hypertension reduces the risk of stroke by 40% and every 20/10 mmHg incremental increase in systolic blood pressure (SBP) and diastolic blood pressure (DBP) above115/75 mmHg doubles the risk of stroke[4]
We reported that the 10-year probability of stroke by the Framingham risk score in hypertensive Korean patients was approximately 1.7 times higher than of the risk of stroke in of the Korean Cancer Prevention Study (KCPS) cohort[10]
Summary
The purpose of this study was to investigate the pattern of distribution of risk factors for stroke and the 10-year probability of stroke by the Framingham risk score in hypertensive patients visiting private clinics vs. tertiary hospitals. We reported that the 10-year probability of stroke by the Framingham risk score in hypertensive Korean patients was approximately 1.7 times higher than of the risk of stroke in of the KCPS cohort[10]. This study population was derived from a highly selected group of patients who were attending private clinics and the results did not reflect the real 10-year probability of stroke in Korean hypertensive patients. We set out to determine the 10-year probability of stroke in hypertensive patients attending tertiary hospitals in addition to private clinics using the Framingham risk score and we planned to compare the 10-year probability of stroke by the Framingham risk score between the two groups
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