Abstract
Aim: Electron, photon or proton beams are used in radiotherapy for cancer treatment while each one may be used depending on depth and the location of tumor and normal tissues around the treatment target as well as economic issues. Materials and Methods: In this research, dose distribution by proton was measured by film dosimetry in nasal cavity Plexiglas phantom and Monte Carlo simulation. Then the DVH of treatment target and the posterior of treatment target of different beams were compared. The energies of electron, photon and proton were 9 MeV, 6 MV, and maximum 65 MeV, respectively. Due to a depth of 3.5 cm of CTV (Clinical Target Volume), Modulation Range was between 0 - 3.5 cm and SOBP (Spread-out Bragg Peak) was between 0 - 65 MeV. Results: Comparing the obtained DVH values, 95% dose coverage of target volume for electron, photon, proton and Photon-Electron beams were 88%, 98%, 98%, and 95%, respectively. However, doses above 40% that reached outside the target were 50%, 82%, 5%, and 44%, respectively. Conclusions: The results demonstrate the superiority of proton therapy in nasal cancer due to its better target volume coverage and the less amount of the dose reaching outside the target that is because of dose discharge in a small area and significant dose fall-off after Bragg peak.
Highlights
Aim: Electron, photon or proton beams are used in radiotherapy for cancer treatment while each one may be used depending on depth and the location of tumor and normal tissues around the treatment target as well as economic issues
The results demonstrate the superiority of proton therapy in nasal cancer due to its better target volume coverage and the less amount of the dose reaching outside the target that is because of dose discharge in a small area and significant dose fall-off after Bragg peak
As can be seen from this table, the best coverage of clinical tumor volume (CTV) is for 6 MV photon and 0 - 65 MeV protons, but, the maximum doses to the normal tissues irradiated by 6 MV photon (82%)
Summary
Depending on the position and depth of a tumor, electron, photon, mixed elec-. For shallow-seated lesions, in this study nasal-cavity lesions, the most common method for treatment is using electron beam, because of its low penetration depth and sparing the beyond organs from receiving the radiation dose. Some investigation has been performed about comparison of mixed electron-photon beam and conventional methods [1] [2] [3]. These studies showed that the mixed beam has some advantages over electron or photon beams. The electron beam is more sensitive to small fields [4] [5] than mixed or photon beams
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
