Abstract
Rheumatoid arthritis (RA) is a common autoimmune disease that causes complex immune responses. The pathogenesis of RA is complicated by the involvement of multiple cells, including innate and adaptive immune cells, making treatment difficult. Traditional Chinese medicine (TCM) and therapies differ from western protein-based drugs in the treatment of RA. When several Chinese herbals are normally used to treat RA in TCM, they are primarily targeted at some pro-inflammatory cytokines, such as interleukin 6 (IL-6) and interleukin 1 (IL-1). This project is investigating the mechanisms of several TCM and protein-based drugs. The effectiveness of traditional Chinese therapies such as acupuncture, tuina, and Chinese messages is also evaluated. Besides, the adverse effects and toxicity of researched drugs are listed, and the combination of Chinese medicines and modern pathologies are discussed, aiming to evaluate the effectiveness of TCM for treating RA using modern technologies and medical procedures.
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