Comparing digital light processing and stereolithography vat polymerization Technologies for antimicrobial 3D printing using silver oxide as an antimicrobial filler

Abstract

AbstractVat polymerization technology allows filler particles to be incorporated into photosensitive 3D printing resin to improve the properties of the printed material. This method can be used to produce medical devices with an antimicrobial effect that can reduce biofilm formation and reduce infections due to indwelling devices. Metal oxides have the potential to combat antibiotic‐resistant bacteria, further lowering the risk of hospital‐acquired infections. The antimicrobial agent in this study, silver oxide, was evaluated for its antimicrobial effect against gram‐positive bacteria (Staphylococcus epidermidis) as these are the main cause of biofilm formation. The 3D printed samples demonstrated a strong antimicrobial effect at low concentrations of 1 wt.%. Two vat polymerization technologies, stereolithography (SLA) and digital light processing (DLP), were compared for their suitability for producing 3D printed samples with an antimicrobial effect. DLP successfully produced samples with mechanical properties comparable to the base resin, whereas SLA samples had reduced mechanical strength at higher concentrations of silver oxide filler. Neither printing technology nor silver oxide concentration had a statistically significant effect on the mechanical properties of the printed materials.