Abstract
Background We compare eight reported methods (1-8) for the analysis of cardiac perfusion flow in 3 Tesla MRI on a porcine model. Therefore, an anaesthetized healthy minipig was repeatedly scanned (x5) with a 14 day interval with Turbo FLASH at 3T. The data obtained from the images consists of the temporal course of the arterial input function (AIF) and of the tissue response function (TRF). We compared 8 analysis methods by statistical evaluation of determined perfusion flow. The analysis methods investigated were Fermi function (1), Modelfree Deconvolution (2), Modified Tofts (3), Exchange (4), Uptake (5), Tofts (6), Patlak (7), and Maximum Slope (8).
Highlights
We compare eight reported methods (1-8) for the analysis of cardiac perfusion flow in 3 Tesla MRI on a porcine model
We investigated numerically the throughput of noise in the tissue response function (TRF) on the analysis methods 1-4
Repeatability of the results - independent on the analysis methods - was bad, which is due to the movement of the septum
Summary
We compare eight reported methods (1-8) for the analysis of cardiac perfusion flow in 3 Tesla MRI on a porcine model. An anaesthetized healthy minipig was repeatedly scanned (x5) with a 14 day interval with Turbo FLASH at 3T. The data obtained from the images consists of the temporal course of the arterial input function (AIF) and of the tissue response function (TRF). We compared 8 analysis methods by statistical evaluation of determined perfusion flow. The analysis methods investigated were Fermi function (1), Modelfree Deconvolution (2), Modified Tofts (3), Exchange (4), Uptake (5), Tofts (6), Patlak (7), and Maximum Slope (8)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
