Comparative therapeutic efficacy of hypertonic saline solution andisotonic normal saline for fore-stomach impaction disorders in buffaloes (Bubalus bubalis)

Abstract

The aim of present investigation was to evaluate the comparative therapeutic efficacy of isotonic (0.9%) saline solution (NSS) and hypertonic (7.5%) saline solution (HSS) along with supportive medical treatment in buffaloes suffered with forestomach impaction. A total of 26 buffaloes were undertaken in two groups. In Group 1, twenty buffaloes were infused with isotonic (0.9%) saline solution 20 ml/kg body weight and in Group 2 six buffaloes were infused with hypertonic saline solution (7.5%) 2 ml/kg. The physical parameters (heart rate and respiration rate) were decreased more significantly in Group 1 after treatment. Similar trend was observed in the pretreatment hematological parameters viz. Hb, PCV, TLC, neutrophil count and ESR after fluid therapy which was indicative of expansion of plasma volume. There was not much effect on rumen liquor parameters after fluid therapy. The biochemical profile (Aspartate aminotransferase (AST), Alkaline phosphatase (ALP), bilirubin, Blood Urea Nitrogen (BUN), creatinine, total protein, glucose, globulin and fibrinogen) was more significantly declined in Group 1 after fluid therapy, whereas plasma sodium and chloride levels significantly increased, and plasma potassium level more significantly decreased in Group 2. The recovery rates were 60% and 17% respectively in Group 1 and Group 2. Thus, Isotonic (0.9%) saline solution appears to more effective in therapeutic management of forestomach impaction in buffaloes.