Comparative study on the utilization of antibacterials in perioperation for obstetrics and gynecology

Abstract

Objective To investigate utilization of in perioperation for obstetrics and gynecology after issuing of notice by general office of Ministry of Health further strengthen in management of clinical application of antibacterials. Methods According to survey on use of antibacterials, 272 cases of surgical patients from April to December 2007 (treatment group) and 270 cases ofsurgical patients from April to December 2008 (control group) in obstetrics and gynecology department were selected,the utilization after application of were investigated and compared. Results The utilization rate of prophylactic use of in treatment group and control group were 83.09% (226/272), 84.44%(228/270) respectively (P>0.05). Preoperative use were 77.94%(212/272), 85.19% (230/270) respectively (P 0.05). Both used intravenous as main administration route, double therapy used as major drug combination. Conclusions Comparison of utilization of in perioperation for obstetrics and gynecology before and after enforcement of the guiding principle of clinical use of antibacterials and further strengthen in management of clinical application of antibacterials issued by general office of Ministry of Health. The utilization of exist some defects:remains high starting point for administration;without an additional if operative time exceed three hours;longer administration time and double therapy as major drug combination. In summary,there still are some deficiencies that needs co-management and improvement Key words: Obstetrics and gynecology department, hospital; Intraoperative period; Anti-bacterial agents; Comparative study