Comparative study of ultrasound characteristics on microinvasive breast carcinoma, ductal carcinoma in situ and invasive ductal carcinoma

Abstract

Objective To investigate the ultrasound characteristics of microinvasive breast carcinoma(MBC), and to improve its detection rate. Methods Sixty-five MBC, 85 breast ductal carcinoma in situ(DCIS) and 99 breast invasive ductal carcinoma(IDC) confirmed by pathology were divided into mass type and ductal type according to ultrasonic manifestaions, and the ultrasound characteristics were retrospectively analyzed. Results MBC showed 89.23%(58/65) mass type with 64 lesions and 10.77%(7/65) ductal type.DCIS showed 88.24%(75/85) mass type with 78 lesions and 11.76%(10/85) ductal type. IDC group showed all mass type with 102 lesions. In MBC, most mass type lesions were solid and hypoechoic with a mean maximum diameter, which was larger than DCIS, but similar with IDC(P>0.05). More mass type lesions with irregular shape and calcification were found in MBC than in DCIS(P 0.05). The detection rate of spiculate margin in mass type lesions of MBC was higher than DCIS(P 0.05). More ductal type lesions displayed indistinct duct wall in MBC than DCIS(P<0.05). Meanwhile, MBC had a higher detection rate of internal blood flow(grade 2-3) than DCIS. Conclusions There are more lesions with large diameter, irregular shape, short spiculate margin and calcification in MBC than DCIS. Compared with IDC, MBC lesions are atypical in spiculate margin, and less lesions show hyperechoic halos and high A/T ratio. To be familiar with ultrasound characteristics of MBC is significant for improving its ultrasound detection rate. Key words: Ultrasonography; Breast neoplasms; Microinvasive breast carcinoma