Comparative study of ultrasonic and pathologic features of ovarian teratoma

Abstract

Objective To compare the sonographic and histopathological features of ovarian teratoma. Methods The sonographic and histopathological features were retrospectively analyzed and summarized in 35 cases of patients (40 cases of ovarian teratomas) with ovarian teratoma proved by surgery and pathology in Fuxing Hospital, Capital Medical University from January 2005 to December 2013. Results There were three types on ultrasound: the cystic type (10/40, 25.0%), the solid type (5/40, 12.5%), and the cyst-solid type (25/40, 62.5%). The histopathological findings of the tumors were classified into two types: ovarian mature teratoma (36/40, 90.0%) and ovarian immature teratoma (4/40, 10.0%). In the ovarian mature teratoma group, the majority of the tumor were filled with oil, hair, skin and its appendages. The ovarian struma (1/40, 2.5%) could also be seen in this type, which was mainly filled with thyroid tissue.In the ovarian immature teratoma group, immature tissue mainly consisted of the primitive neural tube under the similar histopathological background with mature teratoma. In comparison of ultrasonography and pathology, the ultrasonographic features of immature teratoma and mature teratoma were similar. Both of them appeared as the solid type and the cyst-solid type. Conclusions In comparison of ultrasonography and pathology, ovarian teratoma′s internal echo and its tissue structure are closely correlated. The cystic type was usually found in mature teratoma, and the solid type and the cyst-solid type can be found in either mature teratoma or immature teratoma. Key words: Ultrasonography; Ovarian tumor; Teratomas; Pathology