Comparative Study of Total Intravenous Anaesthesia Using Propofol with or without Sufentanil in Laparoscopic Cholecystectomies

Abstract

Background: Total intravenous anaesthesia (TIVA) is a ideal substitute to inhalation anaesthesia because ofhemodynamic complications. TIVA with suitable combination of anaesthetic drugs will have good post-operativeresults.Method: 60 patients aged between 18 to 65 years undergoing laparoscopic cholecystectomies were studied. Sixtypatients classified in three groups, 20 patients in each group. GroupsS1 and S2 received propofol with sufentaniladded at 1μgml and 2 μg ml concentration respectively while group P received propofol without sufentanil.Additional sufentanil boluses (10 μg) were when there is an increase in the hemodynamic parameters, recoverytimes, and post-operation analgesia g were compared in all three groups of patients.Results: Hemodynamic parameters (HR, SBP, DBP) were not significantly different in all three groups. Fewer S2patients required additional sufentanil boluses to maintain proper hemodynamic status. S2 group had better postoperativeanalgesia (p<0.001) but prolonged recovery time as compared to other two groups.Conclusion: Sufentanil mixed with propofol provides better hemodynamic stability in laparoscopiccholecystectomies where more chances of pneumothoraxdue to fluctuations in hemodynamic parameters whichmay lead to morbidity and mortality.