Comparative study of three dimensional dynamic contrast-enhanced MR perfusion imaging in healthy volunteers and patients with chronic obstructive pulmonary disease

Abstract

Objective To prospectively compare MR pulmonary perfusion imaging with quantitative HRCT for the detection of mild chronic obstructive pulmonary disease (COPD) and classification of COPD. Methods Sixty-two consecutive patients with COPD and 17 healthy volunteers underwent pulmonary function test (PFT),HRCT and MR perfusion imaging on the same day.According to the Global Initiative for Chronic Obstructive Lung Disease (GOLD),all COPD patients were classified into 4 stages:stageⅠ (n=19),stageⅡ (n=17),stageⅢ (n=14),stageⅣ Key words: Pulmonary disease,chronic obstructive; Respiratory function tests; Magnetic resonance imaging; Tomography,X-ray computed