COMPARATIVE STUDY OF THE UTERINE TUBES SMOOTH MUSCLE MORPHOPHYSIOLOGICAL ORGANIZATION IN ECTOPIC PREGNANCY AND IN HEALTHY NONPREGNANT WOMEN

Abstract

Smooth muscle cells (SMC) of the human uterine tube isthmus have been studied in two groups — healthy nonpregnant women who underwent surgical sterilization and patients with ectopic (ampullar) pregnancies. The method of target cell dissociation was used. An analysis was performed using the methods of morphometry and quantitative histochemistry (including the analysis of nuclear DNA content, and cytoplasmic protein content). Three types of myocytes with different structural-metabolic parameters have been revealed. The comparative analysis of intact and affected SM of the tubal isthmus demonstrated changes in the structure of leiomyocytes population, optic density of cytoplasmic protein and proliferative activity of myocytes.