Abstract
Aim: To investigate the efficacy of two corpus luteum support programs in patients with frozen embryo transfer (FET). Methods: A retrospective analysis of the complete clinical data of 340 patients undergoing in vitro fertilization embryo transfer in the Department of Reproductive Medicine, Jingzhou Central Hospital from September 2016 to July 2018. These patients were divided into group A and B according to the luteal support program. We compared the clinical outcomes of the two corpus luteum preparations by comparing the laboratory parameters of the two groups of patients with clinical pregnancy indicators. Results: We found there was no significant difference in the results of general conditions in the two groups of patients, such as infertility age and duration, body mass index (BMI), basal follicle stimulating hormone (FSH), basal luteinizing hormone (LH), basal estrogen (E2) levels, the endometrial thickness, the number of transplanted high-quality embryos on the day of transplantation and so on (P > 0.05). We found that the implantation rate (32.55%), biochemical pregnancy rate (53.57%), and clinical pregnancy rate (51.78%) in group B were significantly higher than those in group A (25.26%, 35.11%, and 34.66%, respectively) (P 0.05). Conclusion: We conclude that patients who are scheduled for frozen embryo transfer use progesterone vaginal sustained release capsules combined with luteal progesterone luteal support, have improved clinical pregnancy rates.
Highlights
Since the development of self-assisted reproductive technology, it has solved the fertility problem of many patients
We found there was no significant difference in the results of general conditions in the two groups of patients, such as infertility age and duration, body mass index (BMI), basal follicle stimulating hormone (FSH), basal luteinizing hormone (LH), basal estrogen (E2) levels, the endometrial thickness, the number of transplanted high-quality embryos on the day of transplantation and so on (P > 0.05)
We conclude that patients who are scheduled for frozen embryo transfer use progesterone vaginal sustained release capsules combined with luteal progesterone luteal support, have improved clinical pregnancy rates
Summary
Since the development of self-assisted reproductive technology, it has solved the fertility problem of many patients. With the development of society, frozen embryo transfer (FET) technology has become an important supplement to in vitro fertilization embryo transfer (IVF-ET) technology and it is important to improve the pregnancy rate of patients [1]. Since the patients themselves cannot produce the corpus luteum during the hormone replacement cycle, the support program of corpus luteum before and after transplantation is a very important link, which is of great significance for improving endometrial receptivity and increasing pregnancy rate. In order to explore the corpus luteum support program to improve the pregnancy rate of freeze-thaw embryo transfer, this study is mainly through retrospective analysis. In order to explore the luteal support program to improve the pregnancy rate of frozen-thawed embryo transfer, this study retrospectively analyzed the efficacy of two corpus luteum support programs in patients undergoing frozen embryo transfer to explore appropriate methods to meet the needs of patients
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
