Abstract

In this study, we report the first preparation of a series of lactose-derived acylhydrazone compounds with alkyl side chains ranging from 5 to 10 carbons in length through condensation reactions as a new type of nonionic surfactants. The surface-active, foaming properties, emulsifying properties, thermal stability as well as cytotoxicity were studied to establish the structure-property profile, which revealed that the acylhydrazone derivatives bearing medium-length side chains had better overall performance than their analogs and other selected commercial references. The results could serve as basis for the further development of lactose-derived acylhydrazones as emulsifiers in, for example, food and pharmaceutical industries.

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