Abstract
152 The oxidative stress of an organism is a result of the acceleration of lipid peroxidation (LPO) in cells and the formation of reactive oxygen species and free rad icals. This process leads to destruction of membranes, the emergence of numerous pathologies, and prema ture aging of the organism. The search for new antiox idants, as well as for methods to assess the antioxidant activity, is an important and interesting task [1]. Of particular interest are synthesis and study of properties of polyfunctional compounds with several pharma cophoric centers in the molecule, because such a com bination is able not only to enhance the known physi ological activity but also to cause the appearance of new types of physiological activity [2–4]. Ionol I (2,6 di tert butyl 4 methylphenol) is a known anti oxidant used in the manufacture of foodstuffs (food additive E321). 2,6 Diisobornyl 4 methylphenol (dibornol) IV is currently undergoing preclinical tri als as a promising drug [5]. CHEMISTRY
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