Abstract
Geriatric population (> 60 years) is rapidly increasing in India, It has been increased upto 8.6% in 2011. Diabetes Mellitus (DM) is a metabolic disorder and a major health problem, a?ecting a large section of the Indian population, especially as its incidence increases with advancing age. Host of complications are associated with this disease, one of which is the e?ect on platelet count. This study compares platelet count between diabetic and non-diabetic elderly. It is observed that Hyperglycaemia in diabetic persons is responsible for increased Thrombopoietin production at the cellular level, which leads to raised platelet count -Reticulated Thrombocytosis – when compared to non diabetics. Platelets, especiallyreticulated thrombocytes are associated with uncontrolled blood sugar levels in the body and are well known for their role in artherosclerotic cardiovascular disease (CVD).
 Keywords: platelet count, diabetic and non-diabetic & geriatric.
Highlights
Geriatric or elderly age group faces lot of challenges, both physiological and pathological
There are the associated morbidities of chronic diseases, of which the most notorious one could probably be Diabetes Mellitus
Incidence of Diabetes increases with advancing age
Summary
Geriatric or elderly age group faces lot of challenges, both physiological and pathological. Diabetes is one of the diseases which directly affect aging systems Both the incidence and the prevalence of diabetes mellitus increase with aging. It is a disease associated with a chronic inflammatory state in the body. Pluripotent Hematopoietic stem cell (HSC) converted into Megakaryocyte-Colony Forming Unit. This committed cell line develops into platelets after passing through 3 stages, which include: 1.MEGAKARYOBLAST– Earliest recognizable precursor cell, large size, has a large oval nucleus with several nucleoli. Formation takes about 10 days and is regulated by Colony stimulating factors and a circulating protein hormone (TPO) THROMBOPOEITIN which increases platelet production. Aims and Objectives of the Study: To compare the platelet count of elderly diabetics with nondiabetics
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