Abstract
Purpose To Compare the extent and intensity of adhesions formed between the intra-abdominal organs and the intraperitoneal implants of polypropylene mesh versus polypropylene/polyglecaprone versus polyester/porcine collagen used for correction of abdominal wall defect in rats.Methods After the defect in the abdominal wall, thirty Wistar rats were placed in three groups (ten animals each) for intraperitoneal mesh implant: polypropylene group, polypropylene/polyglecaprone group, and polyester/porcine collagen group. The macroscopic evaluation of the extent and intensity of adhesions was performed 21 days after the implant.Results The polypropylene group had a higher statistically significant impairment due to visceral adhesions (p value = 0.002) and a higher degree of intense adherence in relation to polypropylene/polyglecaprone and polyester/porcine collagen groups (p value<0.001). The polyester/porcine collagen group showed more intense adhesions than the polypropylene/polyglecaprone group (p value=0.035).Conclusions The intraperitoneal implantation of polypropylene meshes to correct defects of the abdominal wall caused the appearance of extensive and firm adhesions to intra-abdominal structures. The use of polypropylene/polyglecaprone or polyester/porcine collagen tissue-separating meshes reduces the number and degree of adhesions formed.
Highlights
The incisional abdominal hernia can be defined as a hernia protrusion that develops in the topography of a previous surgical incision or a traumatic injury to the abdominal wall
The repair of large abdominal wall hernias is technically challenging. It is associated with a long hospitalization, difficulties and complications in the healing process, intra-abdominal hypertension, high rate of re-operations, readmissions and hernia recurrences, with a consequent increase in overall costs of treatment[1,6,7]
There were postoperative complications, with emphasis on partial dehiscence of the operative wound, which was diagnosed between postoperative D7 and D9
Summary
The incisional abdominal hernia can be defined as a hernia protrusion that develops in the topography of a previous surgical incision or a traumatic injury to the abdominal wall. It is one of the most frequent complications after elective or emergency abdominal surgeries. The repair of large abdominal wall hernias is technically challenging It is associated with a long hospitalization, difficulties and complications in the healing process, intra-abdominal hypertension, high rate of re-operations, readmissions and hernia recurrences, with a consequent increase in overall costs of treatment[1,6,7]
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