Comparative study of nonalcoholic fatty liver disease diagnosed by ultrasonography with lipid profile and body mass index in young adults

Abstract

Background: Obesity individual have increased BMI and abnormal lipid profile. The abnormal lipid profile will causes fatty infiltration in the hepatic cells and it will progress towards to fatty liver. Fatty liver is a benign condition it is identified as a main cause for liver related mortality and morbidity. Liver steatosis by ultrasound grading might throw a warning sign of the future risk.Methods: A cross sectional study, containing 60 young adults. In all the subjects, Height was estimated in centimeters and Weight was measured in kilogram on standard clinical weighing machine. BMI was calculated as Weight in kilogram divided by Height in meters squared. They are classified based on BMI and all the individuals liver ultrasound and lipid profile was performedResults: In the present study most of the high BMI subjects have Grade 2 steatosis followed by Grade 1. In BMI greater than 25 group around 56% are belongs to Grade 2 and Grade 3 whereas in case of BMI less than 25 group it is 16%. There is significantly increase of serum triglycerides, cholesterol, VLDL and LDL in BMI greater than 25 group compared to BMI less than 25. Whereas serum HDL was significantly declined in higher BMI.Conclusion: Present study finding suggested that there is a more staetosis in overweight and obese individuals. Ultrasonography guided liver steatosis is a cost effective, noninvasive, easy and reproducible and early intervention prevent worst prognosis.