Comparative study of Intravenous Dexmedetomidine as Premedication versus supplementation for spinal anaesthesia with Intrathecal 0.75% Isobaric Ropivacaine in elective lower limb surgeries and lower abdominal surgeries

Abstract

Background: Spinal anesthesia is commonly administered intraoperatively. However, relative short duration of action is associated with local anesthetics. A variety of adjuvants is used for prolongation of postoperative analgesia. Aims and Objectives: Comparative analysis of intravenous dexmedetomidine as a premedication and spinal anesthesia treatment with intrathecal isobaric ropivacain of 0.75% in elective lower limb surgery and lower abdominal surgery. Material and Methods: Following approval by the ethical committee, 60 patients scheduled for elective lower limb orthopedic surgery and lower abdominal surgery were chosen and randomized into two groups (n=30). The patient was then intrathecally administered 3 ml amount of 0.75 percent isobaric ropivacaine in lateral location. Another syringe containing dexmedetomidine was given after 10 minutes of placement, for 10 minutes using syringe pump. Comparison of sensory block initiation, analgesic effects and hemodynamic effects was made between the 2 classes. Results: Comparison of age distribution of (P=0.164) was not statistically important. In Group P, the median age was (40.96 ± 15.3 years) and in Group S (44.33 ± 12.66 years).