Abstract

Introduction: Acharya Sushruta, the father of surgery has included Ashmari in Astamahagada due to its fatal nature. “Ashman” the Sanskrit word, literally means “structure resembling stone”. While the word ‘Ari' means ‘enemy,' so it refers to a sickness in which stones grow and inflict intense pain, as if caused by an adversary. Mutrashmari can be associated with Urolithiasis which is the third most common affliction of the urinary tract. Acharya Sushruta has described medicinal treatment in the initial stage of the disease and advised that surgery to be done only on failure of conservative treatment and when death becomes inevitable if not operated. In Yogaratnakar, Ashmari chikitsa, Kutaja is described to be more effective in the treatment of Mutrashmari. Need of study: In modern medicine, the treatment of urinary stones is non surgical as well as surgical interventions but both have some limitations and also stone formation reoccurs after removal. There is a need for safe, cost effective and simple method of management of urolithiasis which is curative as well as preventive. Aim: Comparative assessment of efficacy of Kutaja Beeja Churna and Ayurvedic Herbal Compound in the management of Mutrashmari (Urolithiasis). Materials and Methods: A randomised control trial (single blind parallel) with 1:1 ratio on 2 groups and will be conducted in Mahatma Gandhi Ayurved College Hospital and Research Centre Salod (Hi) Wardha. Expected duration of the study is one and half year (February 2022 - August 2023). Approval from the Institutional Ethical Committee has been taken and for this trial the registration number is CTRI/2021/09/036297. For statistical analysis Wilcoxon signed-rank test, Mann Whitney U test, Student’s t-test and the Statistical Package for the Social Sciences (SPSS) software will be used in the study. After doing drug analysis, a total of 60 patients fulfilling the inclusion criteria will be selected and distributed in two groups having 30 each. In group A, Kutaja Beeja Churna and in group B, Ayurvedic Herbal Compound will be given twice a day for 45 days. Assessment will be done on day 15, 30 and 45 and after the intervention; follow-up will be taken on days 60 and 90. Results will be drawn from the observations of subjective parameters like pain and dysuria and objective parameters like size of the stone, site of the stone and haematuria.

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