Comparative study of efficacy of Khanduchakka (Ehretia laevis) Ghrit and cow ghee in the management of Parikartika (fissure in ano)

Abstract

Background: Fissure in ano a very common anorectal disorder can be compared with Parikartika as per Ayurveda. Khanduchakka (Ehertia laevis) has Vraņashodhana and Ropaņa (wound-healing) properties that can help to heal the Vraņa (ulcer) rapidly. Its base is ghee, which itself has Samskaranuvarti (i.e., enhancing the properties of a drug) and healing properties. Khanduchakka Ghrita is beneficial by virtue of easily available ingredients and a time-tested classical formulation. Hence, it was compared with cow ghee in this study. Aim: Evaluation of the efficacy of Khanduchakka Ghrita, compared with cow ghee, in the management of Parikartika.Materials and Methods: Diagnosed cases of fissure in ano as per the inclusion and exclusion criteria were selected and divided into two groups. For patients in group A, Khanduchakka Ghrita was applied; and in group B, cow ghee was applied. Assessment of each patient was carried out on 0, 15th, and 30th day and a follow-up on 45th day. Data were collected and a statistical analysis was done using appropriate tests. Results: The present study found that pain, itching, bleeding, and tenderness were significantly reduced and healing was significantly faster in group A (n = 15) compared to group B (n = 15). Conclusions: Based upon the results it can be concluded that Khanduchakka Ghrita is more significant than cow ghee in managing Parikartika.