Abstract
Background: Parasitic disease constitutes 60-70% diseases affecting the animals and has serious economic implication in livestock entrepreneurship by direct and indirect production loss. Indiscriminate use of anthelmintic drugs has made the situation even more precarious. A similar problem was encountered in goat from Holidhani, Jhenidah, where goats with complain of intermittent diarrhea and loss of body condition was reported despite of routine deworming.Objective:Â Determining the efficacy of conventional anthelmintics used and its comparison with some unexploited antiparasitic drugs for the same reason.Methods: Sixty-five goats were divided into five groups. Group A goats were kept as the control, Group B (I, II, III), group C (IV, V, VI), group D (VII, VIII, IX) and group E (X, XI, XII) goats were treated with levamisole, albendazole, fenbendazole and ivermectin respectively. All the treated and control goats were kept, housed for 21 days after the first treatment. Fecal samples were collected and counted on 1st, 7th, 14th and 21st day by using McMaster counting method.Results: Among the three doses of levamisole, albendazole, fenbendazole and ivermectin, the doses of 7.5, 7.5, 5.0 and 0.2 mg/kg body weight, body weight were found to be most effective against gastrointestinal nematodes in goats with a maximum reduction of fecal egg count to the extent of 95.38, 97.13, 98.08 & 99.16 percent respectively.Conclusion: The study revealed low efficacy of levamisole and hence ivermectin is a better drug than albendazole and fenbendazole to control gastrointestinal nematodes in goats.Â
Highlights
Bangladesh is one of the most densely populated country in the world with an estimated 1,033 people/km2 (United Nations, 2011)
Asian Development Bank (ADB) report clearly mentioned the loss of productivity of animals in term of mortality, loss of milk, meat, generation loss and loss of reproductive rate due to animal parasite are to the extent of 50% in Bangladesh
The objective of present study was to find out the comparative efficacy of levamisole, albendazole, fenbendazole and ivermectin against gastrointestinal nematodes in goats, maintained at Holidhani village, Jhenaidah district, Bangladesh based on fecal egg count reduction test
Summary
Bangladesh is one of the most densely populated country in the world with an estimated 1,033 people/km (United Nations, 2011). Goat rearing plays very important role in rural economy and could be used as a tool for poverty reduction in Bangladesh. The objective of present study was to find out the comparative efficacy of levamisole, albendazole, fenbendazole and ivermectin against gastrointestinal nematodes in goats, maintained at Holidhani village, Jhenaidah district, Bangladesh based on fecal egg count reduction test. Results: Among the three doses of levamisole, albendazole, fenbendazole and ivermectin, the doses of 7.5, 7.5, 5.0 and 0.2 mg/kg body weight, body weight were found to be most effective against gastrointestinal nematodes in goats with a maximum reduction of fecal egg count to the extent of 95.38, 97.13, 98.08 & 99.16 percent respectively. Conclusion: The study revealed low efficacy of levamisole and ivermectin is a better drug than albendazole and fenbendazole to control gastrointestinal nematodes in goats.
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