Comparative study of different doses of intrathecal nalbuphine as an adjuvant to bupivacaine in subarachnoid block in cesarean section

Abstract

Background: Spinal anesthesia is preferred over general anesthesia by most of the anesthetists in cesarean section as it provides post-operative analgesia. Materials and methods: The parturient were randomly divided two groups of 30 each. Inj. Bupivacaine 2ml with Inj. Nalbuphine 0.75 mg (GROUP A) and 1 mg (GROUP B) diluted till 0.5 ml, making a total volume of 2.5 ml. The onset and duration of sensory and motor blockade, time of absolute and effective analgesia, number of rescue analgesia required in 24 hours, hemodynamic stability and side-effects were noted. Results: Onset time of motor block was significantly prolonged in group A (3.93±0.59) as compared to group B (3.29±0.46). Duration of absolute analgesia (185.74±4.17) and effective analgesia in Group B (197.25±5.58) is higher as compared to group A, thus number of rescue analgesia required in 24hrs is more in Group A (2.03±0.72) as compared to group B (0.77±0.57)Conclusion: 1mg Intrathecal Nalbuphine as an adjuvant to 0.5% hyperbaric Bupivacaine is more efficient in prolonging postoperative analgesia compared to 0.75 mg dose.