Comparative study of degree-based molecular descriptors of cyclodextrins through M-polynomial and NM-polynomial

Abstract

Cyclodextrins are natural oligosaccharides used to increase the solubility of drugs. It has numerous applications in drug discovery, food storage and other fields. Loftsson et al. explained about applications of Cyclodextrins(CDs) in administrating the drugs through various ways. Jansook et al. has given insights into the structure, physicochemical properties and pharmaceutical applications of CDs. In the present work, cyclodextrin and its derivatives such as α, β, γ CDs are studied for which various degree and neighborhood degree-based topological indices are computed through M-polynomial and NM-polynomial respectively and the comparison of the indices for all three types of cyclodextrins are presented which are of great importance in QSPR/QSAR studies.