Abstract
Background: Coronary artery disease (CAD) is one of the most important manifestation of diabetes mellitus. Objectives: To assess the extent of CAD in diabetic and non diabetic patients undergoing coronary angiography. Materials and Methods: 793 patients with suspected CAD, 202 diabetics and 591 non-diabetics were enrolled in the study. All patients underwent coronary angiography. Results: Normal coronaries were more common in non diabetic patients. Age at first presentation in diabetics was earlier as compared to non-diabetics. Diabetic female patients presented as early as third decade of life. Single vessel involvement was significantly more in non diabetics [40.27%] as compared to diabetic patients[19.8%][P= <0.001], while there were statistically no significant differences in double vessel disease in both groups [P= 0.572]. Triple vessel disease were more common in diabetic than non diabetic patients [P= <0.001]. Left main disease, left circumflex coronary artery disease, coronary calcification, diffuse disease and CTOs were more common in diabetic patients. Conclusion: The severity and extent of CAD and incidence of triple vessel disease was significantly high in diabetics when compared to non diabetics.
 Key Words: Coronary angiography; Coronary artery disease; Diabetes mellitus.
Highlights
Coronary artery disease (CAD) due to atherosclerosis is a major cause of death all over the world and is the most common form of heart disease [1, 2]
Effect of diabetes on incidence of CAD in premenopausal years is more marked in diabetics (17%) compared to non diabetics (3.51%) [p=0.0018] [table 2]
Almost 50% of patients in Pradeep Kurmi et al, International Journal of Medical and Biomedical Studies (IJMBS) both groups were at the age between 50 to 70 years, age is an independent common risk factor for CAD in both diabetic and non diabetic patients
Summary
Coronary artery disease (CAD) due to atherosclerosis is a major cause of death all over the world and is the most common form of heart disease [1, 2]. Coronary artery disease (CAD) is one of the most important manifestation of diabetes mellitus. Objectives: To assess the extent of CAD in diabetic and non diabetic patients undergoing coronary angiography. Results: Normal coronaries were more common in non diabetic patients. Single vessel involvement was significantly more in non diabetics [40.27%] as compared to diabetic patients[19.8%][P=
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