Abstract
Background: This study was aimed to determine the children's' blood sugar level in fluid therapy with DSS (dextrose saline serum), RS (ringer serum) and NS 0.9% serums (normal saline 0.9%) and its relationship with the depth of anesthesia in elective surgery.
 Method: This double-blind experimental study was performed with 90 children referred to the surgical ward, including: group A (receiving DSS), group B (receiving NS 0.9%) and group C (receiving RS) that the blood sugar of each group in 5 steps was measured: half an hour before induction of anesthesia, during induction of anesthesia, half and one hour after induction of anesthesia and after complete awakening in recovery. In addition, the monitoring the vital signs, measuring depth of anesthesia, pulse oximetry and electrocardiogram were performed for all groups.
 Results: The results showed that the mean blood sugar in the 5 steps measured had a significant difference in three groups under study (P <0.05). The mean blood sugar in the group receiving DSS was significantly higher than the two groups receiving RS and NS 0.9%. Also the mean depth of anesthesia in three groups did not show a significant difference.
 Conclusion: Finally, according to this study, the use of DSS from the beginning of anesthesia, RS half an hour after the start of anesthesia and NS 0.9% one hour after the start of anesthesia can increase blood sugar in children. Therefore, the use of DSS is not recommended due to the stressful nature of anesthesia and operating room and the possibility of hyperglycemia.
Highlights
Recognition of physiological changes caused by surgery and anesthesia is one of the most important medical advances in recent years [1]
This study was aimed to determine the children's' blood sugar level in fluid therapy with DSS, RS and NS 0.9% serums and its relationship with the depth of anesthesia in elective surgery. This double-blind experimental study was performed with 90 children referred to the surgical ward, including: group A, group B and group C that the blood sugar of each group in 5 steps was measured: half an hour before induction of anesthesia, during induction of anesthesia, half and one hour after induction of anesthesia and after complete awakening in recovery
The results showed that there was a significant difference between the three groups in terms of demographic characteristics, age and weight of children before the study, and the groups were not identical in terms of these variables (P
Summary
Recognition of physiological changes caused by surgery and anesthesia is one of the most important medical advances in recent years [1]. These changes directly affect the cardiovascular system, metabolic, fluid, and electrolyte of the body and lead to increase the risk to the patient [2]. Improper management of diabetes can significantly increase the risk of serious, acute and chronic complications The occurrence of these complications is mainly due to increased blood glucose levels. This study was aimed to determine the children's' blood sugar level in fluid therapy with DSS (dextrose saline serum), RS (ringer serum) and NS 0.9% serums (normal saline 0.9%) and its relationship with the depth of anesthesia in elective surgery. The monitoring the vital signs, measuring depth of anesthesia, pulse oximetry and electrocardiogram were performed for all groups.
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