Abstract
Ajuga bracteosa is native to Himalayan region, Afghanistan, China and Malaysia. People of northern areas of Pakistan call it ‘korri booti’ as it has bitter taste. Ajuga bracteosa is ethnically used against malarial fever, diabetes, cancer, and sore throat. The theme of present work was to appraise the biological significance of Ajuga bracteosa through in vitro studies. n-Hexane, chloroform, and methanol extracts of root and whole plant materials were obtained via maceration. Qualitative and quantitative analysis of phytochemical constituents was done. The antioxidant potency was judged by DPPH (1,1-diphenyl-2-picrylhydrazyl) and ABTS (2,2-azinobis-(3-ethylbenzothiazoline-6-sulphonic acid) free radical scavenging assays. Antimicrobial efficacy was assessed by agar disc diffusion method. Phytochemical review confirmed the existence of flavonoids, saponins, phenols, tannins, terpenoids, xanthoproteins, carbohydrates, and glycosides. Total flavonoid and total phenolic contents were shown as rutin and gallic acid equivalents respectively. Root extracts gave more significant results of DPPH and ABTS potential (100 % and 92 % respectively) as compared to whole plant extracts (90 % and 75 % respectively). A. bracteosa is a plentiful source of polyphenolic compounds. Polyphenolic compounds are thought as natural antioxidants because of their ability of hydrogen atom donation and presence as stable radical intermediates preventing further creation of free radicals in the body. Root extracts showed greater resistance against pathogens as compared to extracts of whole plant material. Keywords: Antimicrobial activity; Antioxidant activity; Medicinal plants; Phytochemical screening http://dx.doi.org/10.19045/bspab.2021.100135
Highlights
Introduction organization had stated that only250 out ofSide effects of synthetic drugs have forced20,000 types of medicinal plants were the medicinal world to return to nature i.e to inspected for their potential against use medicinal plants for healthcare.diseases
Ajuga bracteosa is native to Himalayan region, Afghanistan, China and Malaysia [5]
Our study showed more presence of these compounds in methanolic extracts of root and whole plant materials as compared to chloroform and n-Hexane extracts of the same plant materials
Summary
20,000 types of medicinal plants were the medicinal world to return to nature i.e to inspected for their potential against use medicinal plants for healthcare. Pakistan includes more than 600 medicinal plants and people use these plants for medication purposes against fever, cough, and cold and to heal wounds. People of northern areas of Pakistan call it ‘korri booti’ as it has bitter taste [6]. It belongs to family Labiatae of 266 genera and 301 species [7]. Preparation of extracts Roots were separated from remaining plants body in order to prepare two fractions i.e fraction of root material and fraction of whole plant material (stem and leaves) and crushed into a fine powder. Following formula was used to calculate percent recovery of extracts
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