Abstract
Comparative Study Between the Post Vaccinal Histopathological Alterations in Some Broiler Chickens’ Tissues Induced by Lasota and VG/GA Newcastle Disease Vaccinal Strains
Highlights
Newcastle disease (ND) is one of the most critical avian diseases affecting poultry production (Mousa et al, 2019)
According to the phylogenetic analysis, intravenous pathogenicity index (IVPI), intracerebral pathogenicity index (ICPI), and mean death time (MDT) Newcastle disease virus (NDV) strains are grouped as highly virulent, moderately virulent and avirulent (Sedeik et al, 2019)
Vaccines used in the experiment Commercial LaSota vaccine: Lyophilized vaccine consists of a live, lentogenic NDV, 1000 dose each dose consists of 106 EID50 of vaccinal virus
Summary
Newcastle disease (ND) is one of the most critical avian diseases affecting poultry production (Mousa et al, 2019). ND is caused by Avian orthoavulavirus-1 which has a negative sense single-stranded non segmented RNA genome (Bello et al, 2019). According to the phylogenetic analysis, intravenous pathogenicity index (IVPI), intracerebral pathogenicity index (ICPI), and mean death time (MDT) NDV strains are grouped as highly virulent (velogenic), moderately virulent (mesogenic) and avirulent (lentogenic) (Sedeik et al, 2019). NDV affects about 240 species of birds. The clinical signs of ND depend on the virus strain, host species, environmental stress, co-infection with other microorganisms, and host immune status. ND is characterized by respiratory, nervous, and enteric infections (Gowthaman et al, 2019)
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