Comparative study between multi-detector CT angiography and digital subtraction angiography in evaluation of peripheral arterial occlusive disease

Abstract

ObjectiveThe aims of the study were the evaluation of peripheral arterial occlusive disease with multidetector or multi-slice CT angiography (MDCTA) and comparison of the results with the results of digital subtraction angiography (DSA), a standard reference. Patients and methodThe written informed consent of the patients and ethics committee approval were obtained. The prospective study group consisted of 10 patients complaining of peripheral arterial disease. Using MDCT-A, the arterial tree of the lower extremity was evaluated for the presence of steno-occlusive lesions that might have led to luminal stenosis. The diagnostic accuracy of MDCTA was calculated and compared with that of DSA. ResultsIn the segment-based analysis, the sensitivity, specificity, and accuracy of MDCT angiography in determining significant stenoses were 100%, 99.3%, and 99.6.3%, respectively. The compatibility between MDCTA and DSA methods in grading stenosis was calculated as 0.896 (P<0.007) and it was statistically significant. ConclusionMDCT angiography is significantly compatible with DSA method in the evaluation of peripheral arterial diseases. It is a non-invasive method and can be an alternative to DSA.