Abstract
To study the intraperitoneal use of polyester with collagen and polytetrafluoroethylene meshes in the correction of total ventral wall defects in rats. Thirty two rats were evaluated and divided randomly into four groups and underwent laparotomy and preparation of total defects of the abdominal wall. Next, the correction of the defect with the intraperitoneal placement of the chosen mesh was performed. The rats were submitted to euthanasia at 30 and 90 days after surgery. Were analyzed the macroscopic adhesions and microscopic aspects, and applied stress rupture test All animals showed intraperitoneal adhesions in varying degrees, with no statistical significance difference. There was no difference also between groups in the evaluation of stress rupture tests. On the microscopic aspect, the A30 group had less inflammatory reaction and less formation of granulomas and foreign body reaction that the B30 group, with significant difference. There was no difference in intraperitoneal adhesion and tensile rupture strength among groups. Group B30 presented granulomatous inflammatory reaction at the site of mesh attachment to the wall significantly higher than the A30.
Highlights
IntroductionThe treatment of incisional hernias is with surgery
Hernias are common complications after abdominal surgical procedures, with a prevalence of 11% to 20% and complications can arise from their presence, such as incarceration (6% to 15%) or strangulation of intestinal contents (2%)[1].The treatment of incisional hernias is with surgery
The ventral hernia repair with meshes has resulted in a low rate of recurrences, but when contact with the viscera with the prosthesis can not be avoided, there is a large inflammatory response with peritoneal complications
Summary
The treatment of incisional hernias is with surgery. The use of synthetic prostheses in the repair of hernias began a new chapter in surgical treatment, and can serve both, as reinforcement of a suture or as a substitute for deficient tissues[2]. The most commonly used prostheses are made of polypropylene. They have some disadvantages, such as the formation of intraperitoneal adhesions[3,4], obstructions and intestinal fistulas[5]. The ventral hernia repair with meshes has resulted in a low rate of recurrences, but when contact with the viscera with the prosthesis can not be avoided, there is a large inflammatory response with peritoneal complications. In order to minimize adhesions and maintain resistance, alternatives have been developed for polypropylene, with the introduction of polytetrafluoroethylene, polypropylene/poligalactina, double side polypropylene/ carboxymethyl cellulose and polyester/polyethylene glycolglycerol collagen meshes[6]
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