Comparative study between intrathecal bupivacaine versus intrathecal bupivacaine and fentanyl in elective caesarean sections

Abstract

Background: Intrathecal administration of adjuvant drugs have been used increasingly for increasing the onset, duration and quality of analgesia. This study was designed to compare the efficacy of intrathecal hyperbaric bupivacaine with that of intrathecal hyperbaric bupivacaine with fentanyl for patients undergoing elective caesarean sections. Materials & methods: 50 aged between 15 to 30 years, whose weight is 45 to 80 kg, belonging to ASA class I and II, scheduled for elective caesarean sections were selected and randomized into 2 groups. Group B received 9mg of hyperbaric bupivacaine 0.5% and group BF received 9mg of hyperbaric bupivacaine 0.5% with 10mcg of fentanyl. The onset of analgesia, onset of motor blockade, the duration of sensory blockade, the duration motor blockade, the quality of blockade, duration of analgesia, Intrathecal Injection to delivery time, APGAR SCORE of neonates, hemodynamic parameters of parturient and side effects were recorded. Results: There was significant difference between the two groups in the meantime to onset of sensory anaesthesia (group BF 3.28±0.73mins, group B 3.84±1.06mins; p value=0.009). The onset of motor blockade was similar in both the groups. Excellent block was achieved in 80% patients in group B compared to 100% of patients in group BF.