Abstract
Introduction: Field-in-Field (FIF) and Intensity Modulated Radiation Therapy (IMRT) are two advanced radiation therapy planning techniques. Both of them are being used to achieve the same two related aims which are, to expose the targeted tumor to the full radiation dose and to spare the nearby normal tissues (or organs) from being exposed to high amounts of radiation more than its tolerance dose limits. FIF is a forward planning while IMRT is an inverse planning and FIF is a forward IMRT. Aim: The purpose of this study was to compare between Field-in-Field and IMRT techniques in prostate cancer radiotherapy. Method: A treatment planning system supporting both inverse and forward planning facilities is used. Ten prostate cancer patients were planned with both FIF and IMRT planning techniques. Doses received by the Planning Target Volume (PTV) and Organs at Risk (OARs) were compared in the two methods quantitatively from Dose Volume Histograms (DVHs) and qualitatively from (axial cuts). Results: The results showed that the IMRT planning technique achieved better dose coverage to the PTV than the FIF planning technique but, except RT and LT Femoral Heads, FIF achieved a better protection to the Rectum and the Bladder (OARs) than IMRT. Conclusions: The results showed that the inverse planning based IMRT technique is better and recommended in the prostate cancer radiotherapy than the FIF technique.
Highlights
Field-in-Field (FIF) and Intensity Modulated Radiation Therapy (IMRT) are two advanced radiation therapy planning techniques
Tumor volumes such as gross target volume (GTV), clinical target volume (CTV), and planning target volume (PTV) [11] as well as Organs at Risk (OARs) had been delineated by the physician on each axial slice, and Computed Tomography (CT) slices were transferred to the treatment planning system (TPS)
In forward IMRT planning (Field-in-Field (FIF)), the beam parameters were manually adjusted in a try and error process to achieve a good dose distribution to the Planning Target Volume (PTV) and at the same time to spare the OARs from receiving high doses
Summary
Field-in-Field (FIF) and Intensity Modulated Radiation Therapy (IMRT) are two advanced radiation therapy planning techniques Both of them are being used to achieve the same two related aims which are, to expose the targeted tumor to the full radiation dose and to spare the nearby normal tissues (or organs) from being exposed to high amounts of radiation more than its tolerance dose limits. The FIF technique has been used in the treatment of certain cancers It is a manually based forward intensity-modulated radiotherapy (forward-IMRT) plan for which the calculated dose is adjusted in certain dose distribution areas by designing multiple lower-weighted reduction fields based on the main field [3]-[5]. Intensity-Modulated Radiation Therapy (IMRT) is a radiation therapy technique in which non-uniform fluence is delivered to the patient from any given direction of the treatment beam to improve the composite dose distribution. The intensity files generated are electronically delivered to the linear accelerator (Linac), which is computer controlled, equipped with the required hardware and software to deliver the calculated intensity-modulated beams (IMBs) [8]-[10]
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