Abstract

Objective: To compare clinical outcomes between two first-generation endometrial ablation techniques. Design: Prospective comparative coorte. Setting: Tertiary public hospital, university teaching center. Seventy-three patients with abnormal uterine bleeding unresponsive to clinical treatment submitted to endometrial ablation from October 2011 to September 2013. Methods and Main Outcome Measures: Patients were assigned to either monopolar U-shaped electrode resection with rollerball electrocoagulation (group A, n = 36) or rollerball electrocoagulation alone (group B, n = 37). Mean follow-up length was 359 (280 - 751) and 370 days (305 - 766) in groups A and B, respectively. Bleeding pattern, associated symptoms, failure/success rates were assessed 30, 90, 180 and 360 days post-procedure. Findings: Patient characteristics were similar in both groups (P ≥ 0.05). Surgery duration (mean of 48.5 [±12.0] vs. 31.9 [±5.6] min, P < 0.001) and medium distention use (5.700 mL vs. 3.500 mL, P < 0.01) were decreased in group B. Post-ablation clinical improvement was considerable in both groups. Vaginal discharge incidence after the procedure was lower in group B (30.5% vs. 8.1%, P < 0.05). Hysterectomy rate was 9.6%. Overall success rate was 86.1% and 88.1% in groups A and B, respectively. Conclusions: Endometrial ablation using rollerball electrocoagulation alone may be considered safer than resection with rollerball electrocoagulation, which requires shorter surgical time and less distention medium, and is associated with lower postoperative vaginal discharge incidence. Success rate did not statistically differ between groups, but study parameters in absolute values and percents were superior in group B.

Highlights

  • Abnormal uterine bleeding (AUB) is defined as any deviation from the normal menstrual cycle pattern including changes in the frequency, duration or volume of blood flow [1] [2]

  • Initial medical therapy includes the use of non-steroidal antiinflammatory drugs (NSAIDs), antifibrinolytic drugs, combination oral contraceptives (COC) or oral progestins, levonorgestrel intrauterine system (LNGIUS), and hormone replacement therapy during climacterium [6] [8]

  • The study was approved by the institutional Committee of Research Ethics in 2011 September 5, process number 3966-2011, and written informed consent was obtained from all participants

Read more

Summary

Introduction

Abnormal uterine bleeding (AUB) is defined as any deviation from the normal menstrual cycle pattern including changes in the frequency, duration or volume of blood flow [1] [2]. AUB prevalence is estimated at 11% - 13% and increases with age, reaching 24% in women aged 36 - 40 years [6] [7]. The management for AUB has been widely investigated over the past years with the goals of stopping bleeding or promoting regular menstrual cycles with adequate flow volume, taking into account the patient’s desire for future fertility [1]. Initial medical therapy includes the use of non-steroidal antiinflammatory drugs (NSAIDs), antifibrinolytic drugs, combination oral contraceptives (COC) or oral progestins, levonorgestrel intrauterine system (LNGIUS), and hormone replacement therapy during climacterium [6] [8]. When medications are not effective, surgical treatment might be indicated

Methods
Results
Conclusion
Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.