Comparative study between characteristics of the lung cancer, breast cancer and esophageal cancer distal bone metastases

Abstract

Objective To compare the characteristics of the distribution of bone metastases in lung cancer,breast cancer and esophageal cancer.Methods SPECT bone imaging of the entire body was performed after the injection of 99Tcm-methylene diphosphonate(99Tcm-MDP)in 454 cases.Analyzed the distribution of metastatic bone lesions in upper limbs'middle and distal or the pelvis and lower limbs and the distinction of metastatic bone lesions between different diseases were distinguished.Results Of all the 454 patients,120 cases showed abnormal radionuclide concentration in the region of upper limbs'middle and distal or the pelvis and lower limbs.One thousand three hundreds and three metastatic bone lesions were found in all the patients[893 were in lung cancer(64.4%),36 1 were in breast cancer(27.7%)and 103 were in esophageal cancer(7.9%)].Radioactive uptake in rotor area of femur lesions in these diseases was demonstrated to be of large proportion.Conclusions The result of 99Tcm-MDP bone imaging shows that the distribution of the metastatic bone lesions in lung cancer,breast cancer and esophageal cancer vary from place to place. Key words: Lung neoplasms; Breast neoplasms; Esophageal neoplasms; Neoplasms metastases; Technetium Tc 99m medronate; Whole body imaging