Abstract
Duncan, Bowerman, Hearn and Melampy (1960) and Duncan, Bowerman, Anderson, Hearn and Melampy (1961) first showed that porcine corpora lutea when incubated in an in vitro system can be caused to synthesize progesterone. Since that time a considerable amount of work has been published dealing with the rate of progesterone synthesis by corpora lutea of rats, cows, and women. The significant difference between Duncan’s original work and that dealing with corpora lutea from non-porcine species lay in the fact that both the cow and human corpora lutea responded to the addition to the medium of LH-containing hormones by significant increases in progesterone synthesis while porcine corpora lutea were said to be unable to show such a response. These species differences and the possible causes underlying them were of interest to us.
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