Abstract
The properties of canine parvovirus (CPV) and feline panleukopenia virus (FPLV) were compared by means of physicochemical treatments, biological tests, and experimental infection of domestic dogs and cats or specific pathogen-free (SPF) cats. No distinct difference between CPV and FPLV was observed in their physicochemical properties. The difference between CPV and FPLV in range of host cells and in hemagglutination could be confirmed in this study. Moreover, CPV was inactivated by heating at 80°C for one hour as compared to the inactivation of FPLV at 80°C for 2 hours. The physical map of CPV differed from that of FPLV at both ends of DNA digested with Bgl II and Hind III, though the 2 fragments in central part were common to the viruses. Experimental infection of domestic dogs with CPV or FPLV and domestic cats with CPV produced clinical signs of the disease, while the CPV-inoculated SPF cats did not show any symptoms. However, all the experimental animals, with or without clinical signs, produced hemagglutination-inhibiting antibodies to the virus.
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Schedule a callMore From: Nihon juigaku zasshi. The Japanese journal of veterinary science
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