Abstract
There are presented the results of the application of Raman-scattering spectroscopy method (RS) for the qualitative analysis of rams' heart valves surfaces before and during their decellularization. While analyzing RS spectra, it was found that basic differences appear at wave numbers 812 cm-1, 1062 cm-1, 1340 cm-1 and 1440 cm-1, corresponding to phosphodiester linkage of RNA; OSO-3 corresponds to symmetrical stretching of glycosaminoglycans and chondroitin-6-sulfate; corresponds to deformation mode of proteins and nucleic acids (DNA); proteins, lipids. Optical analysis has shown that while analyzing decellularization on the valves surfaces, the content of glycosaminoglycans, proteins and lipids decreases; retains a high DNA content. It was found that with the aid of entered optical numbers it is possible to control the process efficiency of decellularization of the heart valves.
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