Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: a systematic review and network meta-analysis

Areti Angeliki Veroniki,Elise Cogo,Brenda R Hemmelgarn,Patricia Rios,Ryan Kealey,Heather Macdonald,Sharon E Straus,Brian Hutton,Yaron Finkelstein,Jennifer D'Souza,Fatemeh Yazdi,Emily Reynen,Charlene Soobiah,Andrea C Tricco,Kednapa Thavorn

doi:10.1136/bmjopen-2017-017248

Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: a systematic review and network meta-analysis

Areti Angeliki Veroniki, Elise Cogo + Show 13 more

Open Access

https://doi.org/10.1136/bmjopen-2017-017248

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Journal: BMJ open	Publication Date: Jul 1, 2017
Citations: 157	License type: open-access

Affiliation: St. Michael's Hospital, University of Calgary, Canada Research Chairs, University of Toronto, Ottawa Hospital, University of Ottawa, Hospital for Sick Children, Public Health Ontario, Institute for Clinical Evaluative Sciences

#Credible Interval #Antiepileptic Drugs + Show 8 more

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Abstract

ObjectivesCompare the safety of antiepileptic drugs (AEDs) on neurodevelopment of infants/children exposed in utero or during breast feeding.Design and settingSystematic review and Bayesian random-effects network meta-analysis (NMA). MEDLINE, EMBASE and...

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