Abstract

By means of a micro rolling ball viscosimeter, the change of the viscosity of solutions of two species of human serum lipoproteins, the Lipoprotein B (LpB) and the Lp(a) Liproprotein Lp(a), was studied as a function of the addition of ions such as Na, Mg, Ca and Mn. With Na and Mg both lipoproteins showed no deviation from the normal behavior. The presence of Ca and Mn in its divalent form in solutions of Lp(a) caused a strong increase of the viscosity, leading to precipitation. This effect was enhanced by shear and temperature and progressed with the time. Such a behaviour could not be found with LpB.

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