Abstract
The article is devoted to the study of morphological changes of the adrenal glands in arterial hyperten-sion. Adrenals investigated persons who do not suffer in life and suffering from hypertension during the life of hypertension and died from various causes – is incompatible with the life of a mechanical trauma, cerebral hemorrhage, and acute left ventricular failure. In each case, each of the adrenal glands were assessed: the presence and severity of focal and diffuse mononuclear infiltration, the number of lympho-cytes, monocytes, plasma cells and fibroblasts arranged in the respective zones of the cortex and medulla, the severity of hyperemia and edema of various structural parts, the number of zones cortex and medulla endocrinocytes with pycnotic nuclei in the reticular zone evaluated the distribution of secretory cells with lipofuscin and the degree of saturation of the cytoplasm of the secretory cells, in secretory cells of medul-la evaluated nuclear-cytoplasmic ratio, the severity of vacuolization and basophils cytoplasm revealed a number of regularities of morphological changes depending from the various clinical manifestations of hypertension, defining the ultimate option of dying. At the heart tanatogenesis version are more pro-nounced morphological features hyperfunctions glomerular zone – namely delipidization left and right glands. The beam and netted areas contralateral glands embodiment of dying of a heart compared to the brain, is more pronounced hyperemia. When cardiac variant tanatogenesis more pronounced focal lym-phoid infiltration and vacuolization in secretory cells of left adrenal medulla.
Highlights
The article is devoted to the study of morphological changes of the adrenal glands in arterial hypertension
Adrenals investigated persons who do not suffer in life and suffering from hypertension during the life of hypertension and died from various causes – is incompatible with the life of a mechanical trauma, cerebral hemorrhage, and acute left ventricular failure
Наук, доцент, доцент кафедры патологической анатомии СибГМУ
Summary
СРАВНИТЕЛЬНАЯ МОРФОФУНКЦИОНАЛЬНАЯ ХАРАКТЕРИСТИКА НАДПОЧЕЧНИКОВ ПРИ АРТЕРИАЛЬНОЙ ГИПЕРТОНИИ. Проведено исследование морфологических изменений надпочечников при артериальной гипертонии (АГ). Выявлен ряд закономерностей морфологических изменений в надпочечниках, зависящих от различных клинических проявлений АГ, определяющих в конечном итоге вариант умирания. При сердечном варианте танатогенеза более выражены морфологические признаки гиперфункции клубочковой зоны, а именно – делипидизация в левой и правой железах. При сердечном варианте танатогенеза более выражена очаговая лимфоидная инфильтрация и вакуолизация адреналоцитов мозгового вещества левых надпочечников. Артериальная гипертония (АГ) – один из основных факторов риска, определяющих прогноз заболеваемости и смертности населения России от сердечнососудистой патологии [1]. Ранее было проведено сопоставление клинических проявлений АГ и морфологических параметров надпочечников, отражающих их морфофункциональное состояние при различных вариантах течения и исходах АГ [6]. Цель исследования – провести сравнительное изучение морфологических параметров надпочечников, отражающих их функциональное состояние при различных вариантах течения и исходах артериальной гипертонии
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