Abstract
In addition to their antihistamine effects, H1-receptor antagonists possess pharmacological properties that are not uniformly distributed among this class of drugs, such as antiinfl ammatory effects, antiplatelet activity, supression of respiratory burst of professional phagocytes [1]. In our previous study, we compared the effects of dithiaden and another selected H1-antihistamines on the production of reactive oxygen species (ROS) by stimulated phagocytes [2]. Since the antioxidative effects of H1-antagonists are closely related to their anti-infl ammatory activity, we have compared fourteen H1-antihistamines from different pharmacological generations on the respiratory burst of phagocytes and their antioxidative properties in cell-free systems in vitro.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
