Abstract
Our current study aimed to evaluate and compare the five different brands of Fluconazole tablets that are commercially available in Chennai. The physicochemical equivalence of five brands of Fluconazole tablets was determined through the evaluation of various standard parameters such as weight variation, friability, hardness, disintegration, dissolution rate, and amount of drug present. All the brands were found to be bioequivalent and comply with the official tests for weight variation, friability, disintegration, and dissolution tests. The tested brands showed identical drug release profiles. All the five brands evaluated can be considered as biopharmaceutical and physiochemically equivalent. Therefore, it is safe for the patients to switch over from one brand to another
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