Abstract

Open wounds often involve complex pathophysiological events and, consequently, difficult therapeutic problems [1]. However, our increasing understanding of tissue repair processes has permitted great progress in the treatment of open wounds. To achieve appropriate wound repair it is necessary to consider many parameters [2]. Intrinsic wound factors include: 1 Fibroblasts 2 Collagen deposition 3 Macrophages 4 Bacterial burden 5 pH 6 Angiogenic processes 7 Cellular division, migration and differentiation.

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