Abstract
Three new and two commercially available sugar matrices were comparatively evaluated for several fundamental properties of direct compression powder systems. These properties included: particle size distribution, powder flow (determined by a recording powder flow meter), bulk density and moisture content. The matrices studied were Dipac, Nutab, and California and Hawaiian (C & H) Products A, B, and C. These matrices were formulated in to chewable ascorbic acid, multivitamin, and antacid tablets, and analyzed for: weight uniformity, thickness, diameter, hardness, disintegration, resistance to impact stress, friability, dissolution and effect due to aging.The data obtained showed that the new products (C & H products) were comparable, and in some cases, even superior to the commercially available ones.
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