Abstract
BackgroundIntraocular lenses (IOLs) with different diopter (D) intervals may have different tolerance, and may provide different accuracy of refractive outcome after cataract surgery. The aim of the study is to compare the accuracy of refractive outcome after implantation of IOLs with different D intervals after cataract surgery.MethodsA total of 80 eyes from 40 patients who underwent phacoemulsification with implantation of a 0.50 D interval Akreos AO IOL in one eye and a 0.25 D interval Softec HD™ IOL in the other eye were enrolled. The percentages of eyes with refractive prediction error within ±0.50 D at one month after surgery were compared. To evaluate the effect of the dioptric errors of the IOL itself on refractive prediction error, the percentage of eyes with refractive prediction error within ±0.25 D of the IOL with a standard deviation (SD) of ±0.40 D was compared with that of the IOL with a SD of ±0.11 D through Monte Carlo simulations.ResultsIn this clinical study, the percentage of eyes with refractive prediction error within ±0.50 D by the Haigis formula in the Softec HD™ group (85.0%) was significantly greater than that in the Akreos AO group (57.5%; P = 0.027). In Monte Carlo simulations, all percentages of eyes with refractive prediction error within ±0.25 D by the Haigis and SRK/T formulas in the Softec HD™ group were significantly greater than those in the Akreos AO group.ConclusionsThe IOL with a 0.25 D interval was more accurate than the IOL with a 0.50 D interval in predicting refractive outcome after cataract surgery.Trial registrationCurrent Controlled Trials KCT0002192, Retrospectively registered (Date of registration: 6 January 2017).
Highlights
Intraocular lenses (IOLs) with different diopter (D) intervals may have different tolerance, and may provide different accuracy of refractive outcome after cataract surgery
The IOL with a 0.25 D interval was more accurate than the IOL with a 0.50 D interval in predicting refractive outcome after cataract surgery
This study compared the accuracy of refractive outcomes of IOLs with different diopter intervals (0.50 D versus 0.25 D) in cataract surgery and showed that the IOL with a 0.25 D interval had a postoperative spherical equivalent closer to the target refraction predicted by the Haigis and SRK/T formulas than did the IOL with a 0.50 D interval
Summary
Intraocular lenses (IOLs) with different diopter (D) intervals may have different tolerance, and may provide different accuracy of refractive outcome after cataract surgery. The aim of the study is to compare the accuracy of refractive outcome after implantation of IOLs with different D intervals after cataract surgery. We hypothesized that implantation of IOLs with 0.25 D intervals, a value that is expected to have strict tolerance limits, would produce more accurate refractive outcomes than would IOLs with 0.50 D intervals after phacoemulsification. This study compared refractive outcomes after implantation of 0.25 D interval IOL in one eye and 0.50 D interval IOL in the other eye in patients with bilateral cataract
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