Comparative Evaluation of Push-out bond Strength of Three Endodontic Sealers with and without Amoxicillin-An Invitro Study

Abstract

The purpose of this study was to evaluate the sealing ability of three different root canal sealers with and without amoxicillin, using a push-out bond strength test. Sixty single-rooted extracted human teeth were used for this study. Each tooth was instrumented and irrigated with 5.25% Sodium hypochlorite (NaOCl) and 17% EDTA. The teeth were then divided into six test groups: Gutta percha (GP)/AH Plus (Dentsply, Germany), GP/AH Plus with 10% amoxicillin (TEVA Pharmaceuticals Sellersville, PA), GP/Pulp Canal Sealer EWT (Extended Working Time, SybronEndo Orange, CA), GP/Pulp Canal Sealer EWT with amoxicillin, GP/Apexit Plus, GP/Apexit Plus (Vivadent, Tulsa, US) with amoxicillin. After the sealer was set, the entire root was sectioned into 1 mm thick slices. A push-out bond strength test was performed by using a universal testing machine. The Student's t-test was used to compare the sealer bond strength within the specific sealer test groups and within each sealer at apical, middle and coronal root levels. There was no significant difference between the groups within each sealer (p>0.05) with or without amoxicillin at the same root level. This study demonstrated that the addition of 10% by weight of amoxicillin does not significantly (p> 0.05) change the overall push-out bond strength of three endodontic sealers when compared at the apical, middle, and coronal tooth level.