Comparative Evaluation of Plaque Inhibitory and Antimicrobial Efficacy of Probiotic and Chlorhexidine Oral Rinses in Orthodontic Patients: A Randomized Clinical Trial.

Shreya Shruti Shah,Ethel Suman,Asavari Desai,Supriya Nambiar,Kushan Kishore Dhawan,Bhaskaran Unnikrishnan,Deepa Kamath,Sanchit Mahajan

doi:10.1155/2019/1964158

Shreya Shruti Shah, Ethel Suman + Show 6 more

Open Access

https://doi.org/10.1155/2019/1964158

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Abstract

Background Antimicrobial agents serve as an effective adjunct in plaque control, and chlorhexidine has been the gold standard. However, the philosophy that natural agents are better for children's oral health is on the rise. Probiotic technology represents a breakthrough approach to maintain oral health by utilizing natural beneficial bacteria commonly found in healthy mouths. Aim and Objective To compare efficacy of probiotic and chlorhexidine oral rinses in orthodontic patients. Materials and Methods 30 healthy patients undergoing fixed orthodontic treatment were randomly selected for the study by block randomization and allocation concealment and were divided into three groups: group a, 0.2% chlorhexidine mouthwash; group b, probiotic mouthwash; and group c, a control group. Results Probiotic and chlorhexidine groups had significantly decreased plaque indices as compared to the control group. However, greater improvement was seen in the gingival indices than plaque indices with better results in the probiotic group than the chlorhexidine group. No statistical significance was observed in the streptococcus count of probiotic and chlorhexidine groups at the end of the intervention period. Conclusion The comparison of probiotics to chlorhexidine has proven that probiotics are as effective as chlorhexidine as an adjunctive chemical plaque control agent.

Highlights

Orthodontic tooth movement differs from the physiological tooth movement in that it is a biochemical adaptive response to the application of the orthodontic force with the reorganization of the intracellular and the extracellular matrix, in addition to a change of the local vascularization which in turn leads to the synthesis and the release of arachidonic acid, growth factors, metabolites, cytokines, and various enzymes [1]
Conclusion and Summary is clinical trial has helped us to study the effect of probiotics on the oral health status and gingival status and to evaluate the effect on salivary S. mutans colony count of patients undergoing orthodontic treatment. e comparison of probiotics to chlorhexidine has proven that probiotics are as effective as chlorhexidine as an adjunctive chemical plaque control agent. e probiotic and chlorhexidine groups had significantly decreased plaque indices as compared with the control group at the end of the intervention period
Greater improvement was seen in the gingival indices compared to plaque indices with the probiotic group showing better results than the chlorhexidine group. e study reinforced that, at the end of intervention period, there was significant reduction in the Streptococcus count in the probiotic and chlorhexidine groups. e findings suggest that the probiotic mouth rinse is effective in reducing plaque accumulation and gingival inflammation

Summary

Introduction

Orthodontic tooth movement differs from the physiological tooth movement in that it is a biochemical adaptive response to the application of the orthodontic force with the reorganization of the intracellular and the extracellular matrix, in addition to a change of the local vascularization which in turn leads to the synthesis and the release of arachidonic acid, growth factors, metabolites, cytokines, and various enzymes [1]. From the matrix of the dental plaque, the dextran slime can be depolymerized to glucose for use as a carbon source, resulting in the production of lactic acid within the biofilm (plaque) that decalcifies the enamel and leads to dental caries or bacterial infection of the tooth. To compare efficacy of probiotic and chlorhexidine oral rinses in orthodontic patients. 30 healthy patients undergoing fixed orthodontic treatment were randomly selected for the study by block randomization and allocation concealment and were divided into three groups: group a, 0.2% chlorhexidine mouthwash; group b, probiotic mouthwash; and group c, a control group. Probiotic and chlorhexidine groups had significantly decreased plaque indices as compared to the control group. Greater improvement was seen in the gingival indices than plaque indices with better results in the probiotic group than the chlorhexidine group. Conclusion. e comparison of probiotics to chlorhexidine has proven that probiotics are as effective as chlorhexidine as an adjunctive chemical plaque control agent

Results

Discussion

Conclusion